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Expression of different pathways involved in the PI3K-AKT signaling pathway. Pathways marked in red were overexpressed (1) and green pathways were downregulated (−1) when comparing URBs with DRBs. The main conductors to the activation of the Pi3K-Akt signaling pathway, GF and ECM, were elevated in the DRB samples. In addition, ECM downstream ligands ITG-A and B, together with the common pathway PI3K, were elevated in these samples.
