Table 1.
Effect of exogenous melatonin in PCOS rat model with respect to glucose and hormone parameters in groups.
Groups | Glucose (mg/dl) | Testosterone (ng/mL) | Progesterone (ng/mL) | Estradiol (pg/mL) | LH (mIU/ml) | FSH (mIU/ml) | LH/FSH |
---|---|---|---|---|---|---|---|
Control (CON) | 200 ± 8 | 3.87 ± 0.53 | 29.54 ± 1.56 | 28.7 ± 1.42 | 31.62 ± 2.14 | 32.31 ± 2.32 | 0.9 ± 0.23 |
PCOS | 300 ± 11** | 10.23 ± 0.95** | 12.57 ± 2.32** | 14.63 ± 1.25** | 16.43 ± 1.69** | 17.47 ± 1.58** | 1.7 ± .42 ** |
PCOS + MEL | 222 ± 6** | 4.61 ± 0.63** | 16.59 ± 2.14* | 30.20 ± 0.96** | 29.88 ± 2.45** | 28.25 ± 3.21** | 1.1 ± 0.33** |
MEL | 220 ± 10** | 4.15 ± 0.45** | 20.25 ± 1.96** | 31.52 ± 1.21** | 32.96 ± 2.54** | 33.12 ± 52** | 1.00 ± 0.15** |
Data are Mean ± SEM; N = 6. PCOS vs CON, PCOS vs PCOS + MEL, PCOS vs MEL; Superscripts denotes; *p < 0.05; **p < 0.01; ***p < 0.001.