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. 2023 Jun 5;39(11):3307–3310. doi: 10.1007/s00381-023-06004-0

Table 2.

Vancomycin dose and concentration in the serum and cerebrospinal fluid collected from the extraventricular drain during treatment

Day 4 Day 5 Day 6 Day 8 Day 9 Day 10 Day 12 Day 14 Day 17 Day 20
Serum (mg/L) 7.9 8.4 10.7 20.1 13.7 11.3 15.2 14.6 16.4
CSF (mg/L) 4.6 5.9 3.9 3.9 5.9 6.9
Serum / CSF 0.43 0.29 0.28 0.27 0.42
Dose (mg/kg/d) 80 90 100 75 75 75 72 72 72 70
Cre (mg/dL) 0.19 0.20 0.23 0.28 0.25 0.26 0.26 0.28

CSF cerebrospinal fluid, Cre creatinine