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. 2023 Oct 16;12(10):1540–1549. doi: 10.21037/tau-23-114

Table 1. Characteristics of patients who received ADT, stratified by FSH.

Demographic variables FSH P value
Low/normal (≤8 UI/mL) (N=878) High (>8 UI/mL) (N=661)
Age at ADT (years) 73 [68, 79] 76 [70, 83] <0.0011
Year of ADT start 2009 [2004, 2013] 2007 [2004, 2012] 0.0271
Race, n [%] 0.1162
   Black 307 [35] 195 [30]
   White 473 [54] 377 [57]
   Other 40 [5] 34 [5]
   Unknown 58 [7] 55 [8]
BMI at ADT (kg/m2) 30.1 (26.3, 34.2) 29.1 (25.8, 33.2) 0.0041
CCI at ADT 0.1022
   0–2 252 [29] 165 [25]
   3+ 626 [71] 496 [75]
Primary XRT or RP 111 [13] 98 [15] 0.2162
Grade group 0.3472
   1 201 [23] 144 [22]
   2–3 286 [33] 201 [30]
   4–5 275 [31] 208 [31]
   Unknown 116 [13] 108 [16]
PSA at ADT (ng/mL) 6.6 (2.5, 13.9) 6.5 (2.4, 13.8) 0.8071
Testosterone pre-ADT 0.6222
   <30 ng/mL 183 [21] 136 [21]
   30–299 ng/mL 203 [23] 138 [21]
   ≥300 ng/mL 182 [21] 152 [23]
   Missing 310 [35] 235 [36]
Chemo before ADT 0.0532
   Never 753 [86] 579 [88]
   Before ADT 18 [2] 22 [3]
   After ADT 107 [12] 60 [9]
Months from FSH to ADT 8.4 (3.0, 15.9) 7.9 (3.2, 14.6) 0.1991
CRPC 231 [26] 177 [27] 0.8372
Dead 381 [43] 337 [51] 0.0032

Data are shown as median (Q1, Q3) or n [%]. 1, Wilcoxon; 2, Chi-Square. ADT, androgen deprivation therapy; FSH, follicle-stimulating hormone; BMI, body mass index; CCI, Charlson Comorbidity Index; XRT, radiation therapy; RP, radical prostatectomy; PSA, prostatic-specific antigen; CRPC, castration-resistant prostate cancer.