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. 2023 Nov 13;6:1156. doi: 10.1038/s42003-023-05521-7

Table 3.

Genetic risk score (GRS) associations with sleep traits in UK Biobank.

Trait N (pairs) N SNPs Female spouses Male spouses
Self-report Partial R2 F-statistic Partial R2 F-statistic
Chronotype 47,235 156 0.013 604 0.012 548
Ease of waking up 47,325 79 0.006 273 0.006 278
Sleep duration 47,050 70 0.006 279 0.005 239
Insomnia symptoms 47,369 40 0.004 192 0.003 161
Snoring 45,546 38 0.003 142 0.003 132
Accelerometer-derived
Least-active 5 h timing 3454 6 0.003 8.5 0.006 19.2
Sleep duration 3454 11 0.005 17.2 0.014 48.3
Number of sleep episodes 3454 22 0.014 47.2 0.010 33.2
Sleep efficiency 3454 5 0.001 4.8 0.005 17.3

Estimates for variance explained are adjusted for age, assessment centre, genotyping chip and top 10 principal components