Table 2.
Association analysis between the risk HLA allele of DQB1*06:01 and clinical phenotypes.
| With DQB1*06:01 (n = 38) | Without DQB1*06:01 (n = 30) | P | |
|---|---|---|---|
| Clinical characteristics | |||
| Age of onset (years) | 64 [56–72] | 60 [52–69] | 0.42 |
| Gender (female) | 23 (61%) | 20 (67%) | 0.62 |
| Clinical phenotypes | |||
| CAVB | 18 (47%) | 12 (40%) | 0.63 |
| VT or VF | 16 (42%) | 9 (30%) | 0.33 |
| Sustained VT or VF | 10 (26%) | 7 (23%) | 1.00 |
| LVEF (%) | 45 [33–57] | 46 [35–63] | 0.60 |
| Low LVEF | 24 (63%) | 17 (57%) | 0.63 |
| Cardiac device implantation | 29 (76%) | 20 (67%) | 0.42 |
| Successful corticosteroid therapy | 15 (44%) | 6 (27%) | 0.26 |
CAVB complete atrioventricular block, VT ventricular tachycardia, VF ventricular fibrillation, LVEF left ventricular ejection fraction, Low LVEF the patients with LVEF < 50% in the echocardiography at the enrolment.