Figure 1.

HMGB2 is highly expressed in hepatocellular carcinoma tissues. (A) Representative fields of HMGB2, ZEB1 and vimentin protein expression in HCC samples (n=62, scale bar =50 µm). DAB and hematoxylin staining methods were used to detect cytoplasmic and nuclear staining, respectively. (B) PCR was performed to evaluate HMGB2 mRNA in cancer and para-cancerous tissues (n=62). Student t-test was employed for comparison between groups. HMGB2, high mobility group box 2; HCC, hepatocellular carcinoma; ZEB1, zinc finger E-box binding homeobox 1; T, tumor tissue; N, non-tumor tissue; DAB, 3,3’-diaminobenzidine; PCR, polymerase chain reaction.