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. 2023 Oct 26;15(6):725–756. doi: 10.4168/aair.2023.15.6.725

Table 2. Effective maintenance dose of major component allergen for allergen immunotherapy.

Allergen Author Year Major allergen Effective dose Suboptimal dose
Dermatophagoides Ewan et al.76 1988 Der p 1 11.9 mcg
Haugaard et al.77 1993 7.0 mcg 0.7 mcg
Olsen et al.78 1997 7.0 mcg
Short ragweed Van Metre et al.79 1980 Amb a 1 11 mcg
Creticos et al.80 1985 6 mcg
Creticos et al.81 1989 12.4 mcg 0.6 mcg
Furin et al.82 1991 24 mcg 2 mcg
Grass Varney et al.83 1991 Phl p 5 18.6 mcg
Dolz et al.84 1996 Dac q 5 + Lol p 5 + Phl p 5 15 mcg
Walker et al.85 2001 Phl p 5 20 mcg
Frew et al.75 2006 Phl p 5 20 mcg 2 mcg
Birch Bodtger et al.86 2002 Bet v 1 12 mcg
Khinchi et al.39 2004 3.28 mcg
Cat dander Hedlin et al.87 1991 Fel d 1 17.3 mcg
Alvarez-Cuesta et al.30 1994 11.3 mcg
Varney et al.88 1997 15 mcg
Ewbank et al.89 2003 15 mcg 3 mcg
Nanda et al.90 2004 15 mcg 3 mcg
Dog dander Lent et al.91 2006 Can f 1 15 mcg 3 mcg
Alternaria Horst et al.92 1990 Alt a 1 1.6 mcg
Kuna et al.93 2011 8.0 mcg