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. 2023 Oct 31;14:1274431. doi: 10.3389/fimmu.2023.1274431

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Copyright © 2023 Hou, Li, Yang, Shi, Wang and Gao

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Baseline IL-6, IL-10, TNF-α, NLR and PLR are higher, TLC and LMR are lower in GC patients than in healthy individuals. Dot plots show the difference of baseline blood parameters between healthy volunteers (n = 33) and GC patients (n = 77). The top of the grey box shows the median value. All cytokines except for IL-2 and IL-4 were higher in GC patients, but only in the case of IL-6 (p<0.0001), IL-10 (p<0.0001) and TNFα (p = 0.021) these differences were statistically significant. TLC (p<0.0001) and LMR (p<0.0001) were higher in healthy individuals while NLR(p=0.0085 )and PLR (p=0.0034)were higher in GC patients. Error bars show the interquartile range. *p < 0.05, **p < 0.01, and ***p < 0.001.