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Slc6a13 deficiency reduces the secretion of inflammatory cytokines from infected macrophages through blocking inflammasomes. a, b The activation of inflammasomes (NALP1, AIM2, NLRP3, NLRC4, and Caspase-1) in WT + PmCQ2, KO + PmCQ2, and KO + PmCQ2 + glycine macrophages infected with PmCQ2 for 12 h (n = 4, one-way ANOVA). All data were expressed as means ± SD. *p < 0.05, ***p < 0.001, ****p < 0.0001. SD, standard deviation
