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. 2023 Jul 12;29(22):4530–4539. doi: 10.1158/1078-0432.CCR-23-0079

Figure 1.

Figure 1. Applications of ctDNA monitoring for driving targeted treatments in metastatic colorectal cancer. Different scenarios where ctDNA can effectively parallel therapeutic decision making during mCRC continuum of care. Potential impact in each scenario (1–3) is reported in gray boxes at the bottom and discussed in corresponding chapters of this review. ctDNA, circulating tumor DNA; EGFR, epidermal growth factor receptor; mCRC, metastatic colorectal cancer; MSS, microsatellite stable; TMB, tumor mutational burden. (Adapted from an image created with BioRender.com.)

Applications of ctDNA monitoring for driving targeted treatments in metastatic colorectal cancer. Different scenarios where ctDNA can effectively parallel therapeutic decision making during mCRC continuum of care. Potential impact in each scenario (1–3) is reported in gray boxes at the bottom and discussed in corresponding chapters of this review. ctDNA, circulating tumor DNA; EGFR, epidermal growth factor receptor; mCRC, metastatic colorectal cancer; MSS, microsatellite stable; TMB, tumor mutational burden. (Adapted from an image created with BioRender.com.)