Miller 1970.
Methods | Time frame and location: September 1967 to June 1968 in Iowa City, Iowa (USA) Limited detail about methods Sample size calculation and outcome of focus: no mention |
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Participants | General with N and source: 50 women delivering healthy term infants at city hospital. Inclusion criteria: desire to nurse for 3 months and use oral contraceptives while nursing Exclusion criteria: none specified |
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Interventions | Treatment: COC containing norethindrone 1 mg plus mestranol 80 μg daily for 21 days Comparison: identically‐labeled placebos for 21 days Timing: postpartum day 14; all received COC starting 6 weeks postpartum |
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Outcomes | Measures: lactation duration, milk volume production. Results presented in figures without actual numbers; graphic variations not identified. Assessments: 3 weeks, 5 weeks, and 3 months postpartum |
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Notes | ‐‐‐ | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Not specified |
Allocation concealment (selection bias) | Unclear risk | Not specified |
Blinding of participants and personnel (performance bias) All outcomes | Low risk | Participants and investigators blinded |
Incomplete outcome data (attrition bias) All outcomes | Low risk | Loss to follow‐up: 1 in each arm; 1 discontinuation in placebo arm |