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. Author manuscript; available in PMC: 2023 Nov 14.
Published in final edited form as: Biochemistry. 2020 Feb 11;59(7):831–835. doi: 10.1021/acs.biochem.9b01092

Table 1.

Inhibition of MTANs by PEG Fragments

Ki for HpMTAN (mM)
graphic file with name nihms-1941560-t0005.jpg graphic file with name nihms-1941560-t0006.jpg graphic file with name nihms-1941560-t0007.jpg
25 °C 16 ± 3 2.3 ± 0.2 7.1 ± 3.5
37 °C > 100 13 ± 1 54 ± 19
Ki for SaMTAN (mM)
25 °C 6.2 ± 0.8 2.6 ± 0.5 2.8 ± 0.3
37 °C > 100 27 ± 8 41 ± 9