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Inhibition of IL‐1β release in whole blood upon ex vivo stimulation with LPS. BL, baseline; d, days. Blood samples were obtained from patients treated with either placebo or selnoflast, at various timepoints pre‐ and post‐dosing. Blood samples were treated with LPS for 24 h prior to measurement of IL‐1β levels (in the supernatants). The level of IL‐1β is expressed as the percentage change from baseline (pre‐dose), including standard error bars.
