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. 2023 Oct 18;9(11):2226–2251. doi: 10.1021/acsinfecdis.3c00312

Table 2. Values (in Brackets) of the Three Main Spectroscopic Parameters Obtained from Raman Characterizations, Namely, RC/M, RF, and Rrc, as Measured for Different Omicron Subvariant Samplesa.

RC/M RF Rrc
palmitoylation probability surface hydrophilicity membrane flexibility
BA.1.18 (0.66) BA.1.18 (2.22) XE (0.47)
BA.5 (0.66) BA.4 (1.83) BA.5 (0.44)
BA.2 (0.47) BA.2 (1.76) BA.2 (0.37)
XE (0.14) XE (1.55) BA.2.75 (0.35)
BA.2.75 (0.14) BA.5 (1.42) BA.4 (0.16)
BA.4 (0.10) BA.2.75 (1.16) BA.1.18 (0.04)
a

High values for these spectroscopic ratios represent high palmitoylation probability, high hydrophilicity at the virions’ surface, and high membrane flexibility and bulk capacity, respectively.