Fig. 2.

Placental CHOP protein levels are increased in SGA newborns. Placental GRP78/BiP mRNA (A) and protein (B) levels in the AGA and SGA groups. Placental cell lysate extracts were assayed via western blot analysis with antibodies against phosphorylated IRE (C), phosphorylated eIF2α (D), ATF4 (E) and ATF6 (F). Placental CHOP mRNA (G) and protein (H) levels in the AGA and SGA groups. I GADD34 protein levels. Data (N = 10) are presented as the mean ± SEM. * p < 0.05 versus the AGA group. P-values determined by two-tailed unpaired Student’s t-test