Table 3.

Demographic and clinicopathologic features of the clinically oral erythroplakia-like oral squamous cell carcinoma cases

	Country	Sex/age	Smoking	Alcohol use	Site	Clinical features	Incision biopsy diagnosis/ Diagnosis after excision	Size in mm	Symptoms	Treatment	Follow-up in months	Recurrence of SCC
1	Finland	F/58	No	N/av	T	Mostly well-defined, peripheral minor white areas	SCC (microinvasive)/SCC (microinvasive)	N/av	Smarting, burning sensation	SE	92	Yes
2	Finland	F/73	Never	Yes	BM, G	Well-defined, situated slightly below the adjacent mucosa, peripheral minor white areas	SCC (gingiva)/SCC (gingiva)	35	Smarting sensation, pain radiating to ear and maxillary sinus	SE	59	No
3	Finland	F/48	Yes	Occasionally	FOM	Mostly poorly defined, associated ulceration	SCC/SCC	15 × 25	N/av	SE	5	N/av
4	Israel	F/82	Never	No	BM	Well-defined, sinuous borders	(1) VH with dysplasia, (2) SD/SCC	40	No	SE	N/av	N/av
5	Israel	F/76	Never	No	T	Well-defined, peripheral minor white areas	(1) SD, (2) CIS/SCC	30	Pain	SE	24	No*
6	Israel	F/69	No	No	HP	Well-defined, minor ulceration around the periphery	SCC/SCC	15	N/av	SE	12	No
7	Italy	F/80	Never	No	HP	Well-defined, situated below the adjacent mucosa	SCC/SCC	20 × 35	Dental mobility	N/av	N/av	N/av
8	Italy	F/79	Never	No	G	Mostly well-defined, sinuous borders, easy bleeding, associated ulceration	SCC/SCC	20 × 35	Burning sensation, pain	SE	6	N/av
9	Sweden	F/56	Yes	Yes	G	Well-defined, situated below the adjacent mucosa, peripheral minor white areas	SCC/Reactive changes	20 × 10	Smarting sensation	SE	34	Neck metastasis after 20 months

CIS = carcinoma in situ, MiD = mild dysplasia, MoD = moderate dysplasia, SCC = squamous cell carcinoma, SD = severe dysplasia, VH = verrucous hyperplasia

BM = buccal mucosa, FOM = floor of mouth, G = gingiva, HP = hard palate, T = Tongue

SE = surgical excision

N/av = information not available

*Carcinoma in situ after 12 months