Table 3.
Structures and structural predictions of Pel biosynthetic proteins.
| Protein | UniProtKB | PDB code for structure | PDB code for structurally similar protein from DALI search | Function or predicted function | Fold or domains (residues)a | Reference |
|---|---|---|---|---|---|---|
| PelA | Q9HZE4 | 5TCB | 4LY4, 6EZN, 7DD9 | Glycoside hydrolase, deacetylase | Hydrolase domain (47–303), reductase domain (304–506), deacetylase domain (520–800), β-jelly roll (840–946) | Shaik et al. (2011), Wild et al. (2018), Wang et al. (2021) |
| PelB | Q9HZE5 | 5WFT | 6TZK | Pel export | TM helix (19–36), TPR-containing protein (37–877), b-barrel porin (878–1193) | Marmont et al. (2017b), Acheson et al. (2019) |
| PelC | Q9HZE6 | 5T10, 5T11, 5T0Z | Electrostatic funnel | Mixed α/β fold | Marmont et al. (2017a) | |
| PelD | Q9HZE7 | 4DN0, 4DMZ, 4EUV, 4EU0, 4ETZ, 4ETX | C-di-GMP binding protein | GAF domain (181–304), GGDEF domain (321–444) | Li et al. (2012), Whitney et al. (2012) | |
| PelE | Q9HZE8 | 4JHR | Protein interaction | TPR-like protein | Pan et al. (2013) | |
| PelF | Q9HZE9 | 4XSO | GT | GT-B fold | Wang et al. (2016a) | |
| PelG | Q9HZF0 | 6IDS | 12 transmembrane helices | EPS-E subgroup of the MOP transporter superfamily | Kusakizako et al. (2019) | |
| PA4068 | Q9HWW0 | 6WJB, 6WJ9, 6WJA | UDP-N-acetylglucosamine C4-epimerase | N-terminal Rossmann fold (1–173), C-terminal substrate-binding α/β domain (174–309) | Marmont et al. (2020) |
a
Numbering for P. aeruginosa protein.