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. 2023 Oct 4;44(43):4508–4532. doi: 10.1093/eurheartj/ehad653

Table 4.

Echocardiographic Parameters and Relative Cutoffs for TR 5-Tier Grading

Mild (1+) Moderate (2+) Severe (3+) Massive (4+) Torrential (5+)
Qualitative
Tricuspid morphology Normal or mildly abnormal Moderately abnormal Severely abnormal (flail leaflet, large coaptation gap, marked tethering)
Color-flow jet area Small, narrow, central Moderate central Large central, or eccentric, wall impinging
Flow convergence zone Not visible, transient, or small Intermediate in size and duration Large throughout systole
CWD contour Faint, partial, parabolic Dense, parabolic Dense, parabolic or triangular Dense, often triangular, may have low peak velocity Dense, usually triangular, often low peak velocity
Right heart dimensions Usually normal Normal or mild dilatation Usually dilated Dilated
Semiquantitative
VCW (biplane), mma <3 3–6.9 7–13.9 14–20.9 ≥21
PISA radius, mmb ≤5.4 5.5–8.9 ≥9
Hepatic vein flowc Systolic dominant Systolic blunting Systolic flow reversal
Tricuspid inflow (PWD) A-wave dominant Variable E-wave dominant (≥1 m/s)
Quantitative
PISA EROA, mm2 <20 20–39 40–59 60–79 ≥80
Regurgitant volume (2D PISA), mL <30 30–44 45–59 60–74 ≥75
New quantitative methods
Regurgitant fraction, % ≤15 16–49 ≥50
3D VCA, mm2 75–94.9 95–114.9 ≥115
2D Doppler EROA, mm2 75–94.9 95–114.9 ≥115

CWD = continuous-wave Doppler; EROA = effective regurgitant orifice area; PISA = proximal isovelocity surface area; PWD = pulsed-wave Doppler; VCA = vena contracta area; VCW = vena contracta width; other abbreviations as in Table 3.

aAt a color Doppler scale between 40 and 60 cm/s. Note that some studies suggest an average VCW of >9 mm should define severe TR.

bColor Doppler Nyquist shift down toward 20 cm/s, until the hemispherical flow convergence zone is clearly visualized.

cUnless other reason for flow reversal (ie, atrial fibrillation, right atrial elevated pressures/noncompliance). Adapted from: 1) Zoghbi et al16; 2) Lancellotti et al8; and 3) Hahn et al.19