Table 1.
Baseline demographic and clinical characteristics of first 966 GenoVA Study participants with collected biospecimens and the remaining 9,070 eligible members of the VABHS patient population
|
GenoVA patients with collected biospecimens (n = 966) |
GenoVA eligible patients (n = 9,070) |
|||
|---|---|---|---|---|
| Mean | SD | Mean | SD | |
| Age (50–70 years) | 60.47 | 5.65 | 60.68 | 5.83 |
| Body mass index (BMI) | 30.37 | 6.30 | 29.65 | 5.95 |
| Systolic blood pressure (SBP) | 130.1 | 14.45 | 131.03 | 16.22 |
| Diastolic blood pressure (DBP) | 79.74 | 8.73 | 80.00 | 9.49 |
| Low-density lipoprotein cholesterol (LDL-C) | 110.65 | 33.09 | 112.69 | 34.67 |
| n | % | N | % | |
| Gender | ||||
| Femalea | 182 | 18.5 | 1,106 | 12.2 |
| Male | 784 | 81.5 | 7,964 | 87.8 |
| Race | ||||
| American Indian/Alaskan Native | 3 | 0.3 | 35 | 0.4 |
| Asian | 9 | 0.9 | 46 | 0.5 |
| Black/African American | 112 | 11.6 | 1,120 | 12.4 |
| Native Hawaiian/Pacific Islander | 5 | 0.5 | 34 | 0.4 |
| White | 766 | 79.3 | 6,965 | 76.8 |
| Multiracial | 15 | 1.6 | 162 | 1.8 |
| Unknown or declined | 56 | 5.8 | 708 | 7.8 |
| Ethnicity | ||||
| Hispanic of Latino | 53 | 5.5 | 306 | 3.4 |
| Not Hispanic or Latino | 824 | 85.3 | 7,616 | 84.0 |
| Unknown or declined | 89 | 9.2 | 1,148 | 12.7 |
| Ruralityb | ||||
| Rural | 48 | 5.0 | 796 | 8.8 |
| Urban | 917 | 95.0 | 8,269 | 91.2 |
| Area deprivation indexc category (ADI; state rank) | ||||
| Least disadvantaged (ADI 1–3) | 228 | 23.6 | 2,109 | 23.3 |
| Moderately disadvantaged (ADI 4–6) | 359 | 37.2 | 3,363 | 37.1 |
| Most disadvantaged (ADI 7–10) | 364 | 37.7 | 3,466 | 38.2 |
| Unknown or suppressed | 15 | 1.5 | 132 | 1.5 |
Including three transgender women with male biological sex.
Rural or urban designation is attributed to geocoded patient location data as validated by the VA Geospatial Service Support Center. Rural status includes “rural” and “highly rural” designations from VA data. Six individuals included in the total cohort (n = 10,036) have undesignated rurality status.
Area deprivation index (ADI) derived via 2020 FIPS-level ADI, 2020 US Census Block Group shapefile boundaries, and VA Boston Healthcare System (station 523) geocoded patient location data as validated by the VA Geospatial Service Support Center. State rank is based on validated geolocated state of residence. 84.16% of the total cohort (n = 8,446) and 95.24% of participants with collected biospecimens (n = 920) were designated as Massachusetts residents. 147 individuals in the total cohort have missing geolocation data or suppressed ADI designations of high group quarters, low population or housing, both high group quarters and low population or housing, or questionable data integrity.