Table 1.
Study characteristics including the target population, study setting, study focus, US state where the study was conducted, and the BMI criteria (in kg/m2) for each study included in the systematic literature review
| Study | NCT ID | BMI criteria, kg/m2 | Study focus | US states | Study setting | Targeted population |
|---|---|---|---|---|---|---|
| Phase 3 | ||||||
| [31] | NCT00563368 | 30–45 | Drug trial | NC, PA | NR | Healthy |
| [32] | NCT00856609 | > 30 | Drug trial | AZ | Clinical research unit | Nondiabetic, otherwise healthy |
| [33] | NCT01508026 | > 32 | Drug trial | NR | NR | Stage 1 or 2 primary hypertension |
| [41]* | NCT00108459 | ≥ 30 | Diet trial | PA | NR | Diabetes |
| [43] | NCT00696228 | 30–39.9 | Diet trial | TN | Academic medical center | Premenopausal women |
| [48]* | NCT00166205 | Implied** | Surgical procedure trial | NR | Academic and private practice clinical sites | Scheduled for adjustable gastric band surgery |
| Phase 4 | ||||||
| [34] | NCT02160990 | ≥ 30 | Drug trial | MN | Clinical research unit | Accelerated gastric emptying |
| [35] | NCT01834404 | 30–40 | Drug trial | MN | Clinical research unit | Healthy |
| [36] | NCT00791258 | ≥ 30 | Drug trial | NR | NR | Uncontrolled hypertension on monotherapy |
| [37]* | NCT00339833 | ≥ 30 | Drug trial | AZ | Clinical research unit | Nondiabetic |
| [38]* | NCT01035333 | Implied** | Drug trial | Y | Bariatric surgery center | Scheduled for gastric bypass surgery |
| [39]* | NCT02833415 | ≥ 30 | Drug trial | TX | NR | Nondiabetic |
| [40]* | NCT00675987 | 30–40 non-inclusive | Drug trial | CA, FL, IN, MA, Y, PA, TX | NR | Stage 1 hypertension, abdominal obesity, and impaired fasting glucose |
| [45] | NCT00079547 | 30–39.9 | Diet trial | MO | Academic medical center | Nondiabetic |
| [46]* | NCT00143936 | 30 or higher, only included 30–40 | Diet trial | CO, MO, PA | Academic medical center | Healthy |
| Secondary studies | ||||||
| [42]* | NCT00696228 | 30–39.9 | Diet trial | TN | Academic medical center | Premenopausal women |
| [44] | NCT00143936 | 30–40 | Diet trial | COo, MO, PA | Academic medical center | Healthy |
| [47]* | NCT00143936 | 30 or higher, only included 30–40 | Diet trial | CO, MO, PA | Academic medical center | Healthy |
NCT ID, National Clinical Trials registration number; NR, not reported; * phase not reported in the article, but linked NCT ID reported the phase; ** BMI criteria implied due to subjects qualified for gastric band/bypass surgery
This table features the target population, study setting, study focus, US state where the study was conducted, and the BMI criteria (in kg/m2) for each study included in this systematic literature review