Table 4.

Overall response rate.

	Exploratory cohort				Validation cohort
	pMMR		dMMR		pMMR		dMMR
	No. of patients	%	No. of patients	%	No. of patients	%	No. of patients	%
Complete response	26	17.6	0	–	24	16.4	0	–
Partial response	103	69.6	3	25	101	69.2	4	33.4
Stable disease	19	12.8	8	66.7	21	14.4	6	50
Progressive disease	0	–	1	8.3	0	–	2	16.6
ORR	129	87.2	3	25	125	85.6	4	33.4
	p = 0.0114				p = 0.035