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. 2023 Nov 14;7:120. doi: 10.1038/s41698-023-00471-z

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — Ingenuity pathway analysis (IPA) shows a significant enrichment of pathways in MBM compared to ECM (a) and PCM (b). Orange node, enrichment in MBM; blue node, enrichment in ECM or PCM. c Differentially expressed genes (Log2FC; adjusted p < 0.01) in MBM compared to PCM. Only genes that were differentially expressed in MBM compared to both PCM and ECM are shown. Orange bars indicate genes that were upregulated in MBM and blue bars indicate genes that were downregulated in MBM.