Georgiou 1999.

Methods	Controlled trial
Participants	Sixty (60) children, aged 6‐12 years, undergoing minor surgical procedures. No information in abstract as to how these were divided
Interventions	Experimental group: clonidine 4 μg/kg orally, plus atropine Control group: atropine only
Outcomes	Pain by Visual Analogue Scale at 1, 3 and 6 hours postoperatively Need for analgesia
Notes	Abstract does not report pain scores; only reports numbers of children needing analgesia at 1, 3 and 6 hours
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	No information available
Allocation concealment (selection bias)	Unclear risk	No information available
Blinding (performance bias and detection bias) All outcomes	Unclear risk	No information available
Incomplete outcome data (attrition bias) All outcomes	Unclear risk	No information available
Selective reporting (reporting bias)	Unclear risk	No information available
Other bias	Unclear risk	No information available