| Level of evidence and consensus |
|
| 1 |
High level evidence with uniform panel consensus (>85% of votes) |
| 2A |
Lower level evidence with uniform panel consensus (>85% of votes) |
| 2B |
Lower level evidence without uniform consensus (50%-85% of votes) |
| 3 |
Any level evidence but with major disagreement (25%-50% of votes) |
| Treatment preference |
|
| Preferred |
Based on superior efficacy, safety, and evidence and, when appropriate, affordability |
| Alternative preferred |
No definition given |
| Other recommended |
May be somewhat less efficacious, more toxic, or based on less mature data; or significantly less affordable for similar outcomes |
| Useful in certain circumstances |
May be used for select patient populations defined with recommendation |
