Table 1.

Summary of published literature related to single cell analyses in lymphoma

Disease entity	Platforms	Main focus	Authors	Reference
DLBCL	scRNA-seq, cell-free DNA	Biomarkers of CAR T-cell therapy	Deng et al	6
DLBCL	scRNA-seq, bulk RNA-seq	Dissecting cellular heterogeneity	Steen et al	44
DLBCL, follicular lymphoma	scRNA-seq	Intratumor heterogeneity and personalized therapy	Roider et al	43
Follicular lymphoma	scRNA-seq	Subclones of cancer cells and Treg	Andor et al	36
Follicular lymphoma	scRNA-seq	Cancer cells and TFH cells	Haebe et al	38
Follicular lymphoma	scRNA-seq, MC-IF	Nonhematopoietic cells	Abe et al	4
Follicular lymphoma	scRNA-seq, MC-IF	Cytotoxic CD4+ cells and cancer cells with low MHC expression	Han et al	45
GCB cell	scRNA-seq, bulk RNA-seq	Cell of origin (follicular lymphoma)	Milpied et al	40
GCB cell	scRNA-seq, bulk RNA-seq	Cell of origin (DLBCL)	Holmes et al	39
Mantle cell lymphoma	scRNA-seq, bulk RNA-seq	Ibrutinib resistance	Zhang et al	42
DLBCL, CHL	IMC	Spatial classification	Colombo et al	48
CHL	scRNA-seq, IMC	MHC-II expression on HRS cells and LAG3+ Treg	Aoki et al	5
CHL	scRNA-seq, MC-IF	CXCL13+ helper T cells	Aoki et al	41
CHL	CyTOF, TCR	Biomarkers for PD-1 blockade	Cader et al	79
CHL	CyTOF	T-bet+ T cells	Cader et al	76
CHL	MC-IF	PDL1+ macrophages	Carey et al	90
CHL	MC-IF	CTLA4+CD4+ T cells	Patel et al	91
CHL	scRNA-seq, MC-IF	TOX2+CD4+ T cells	Veldman et al	80

CAR, chimeric antigen receptor; DLBCL, diffuse large B-cell lymphoma.