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LS mean CFB in (A) pain VAS, (B) FACIT-Fatigue and (C) CDAI Due to the step-down multiple testing approach, statistical significance was not assessed, or cannot be claimed, for otilimab versus placebo for these endpoints; however, statistical data are provided in the data tables. CDAI, Clinical Disease Activity Index; CFB, change from baseline; FACIT, Functional Assessment of Chronic Illness Therapy; LS, least squares; PBO, placebo; VAS, Visual Analogue Scale.
