| 5.1 Sensitivity analysis: Return to normal hearing, randomised by ear (medium‐term); CC = 0.3 |
1 |
|
Odds Ratio (IV, Random, 95% CI) |
1.13 [0.46, 2.74] |
| 5.1.1 Sensitivity analysis: normal defined as < 15 dB; CC = 0.3 |
1 |
|
Odds Ratio (IV, Random, 95% CI) |
1.13 [0.46, 2.74] |
| 5.2 Sensitivity analysis: Return to normal hearing, randomised by ear (medium‐term); CC = 0.7 |
1 |
|
Odds Ratio (IV, Random, 95% CI) |
1.13 [0.47, 2.75] |
| 5.2.1 Sensitivity analysis: normal defined as < 15 dB; CC = 0.7 |
1 |
|
Odds Ratio (IV, Random, 95% CI) |
1.13 [0.47, 2.75] |
| 5.3 Sensitivity analysis: Return to normal hearing, randomised by ear (medium‐term). Normal defined as < 25 dB; CC = 0.5 |
1 |
|
Odds Ratio (IV, Random, 95% CI) |
1.00 [0.57, 1.76] |
| 5.3.1 Sensitivity analysis: normal defined as < 25 dB; CC = 0.5 (medium‐term) |
1 |
|
Odds Ratio (IV, Random, 95% CI) |
1.00 [0.57, 1.76] |
| 5.4 Sensitivity analysis: Mean final hearing threshold, randomised by ear (medium‐term); CC = 0.3 |
2 |
|
Mean Difference (IV, Random, 95% CI) |
‐3.47 [‐10.01, 3.06] |
| 5.4.1 Sensitivity analysis: correlation coefficient = 0.3 |
2 |
|
Mean Difference (IV, Random, 95% CI) |
‐3.47 [‐10.01, 3.06] |
| 5.5 Sensitivity analysis: Mean final hearing threshold, randomised by ear (medium‐term); CC = 0.7 |
2 |
|
Mean Difference (IV, Random, 95% CI) |
‐3.49 [‐10.37, 3.38] |
| 5.5.1 Sensitivity analysis: correlation coefficient = 0.7 |
2 |
|
Mean Difference (IV, Random, 95% CI) |
‐3.49 [‐10.37, 3.38] |
| 5.6 Sensitivity analysis: Change in hearing threshold from baseline, randomised by ear (medium‐term); CC = 0.3 |
1 |
|
Mean Difference (IV, Random, 95% CI) |
‐0.10 [‐3.22, 3.01] |
| 5.7 Sensitivity analysis: Change in hearing threshold from baseline, randomised by ear (medium‐term); CC = 0.7 |
1 |
|
Mean Difference (IV, Random, 95% CI) |
‐0.21 [‐3.34, 2.92] |
| 5.8 Sensitivity analysis: Adverse event: perforation/retraction, randomised by ear (medium‐term); CC = 0.3 |
1 |
|
Odds Ratio (IV, Random, 95% CI) |
0.85 [0.33, 2.21] |
| 5.8.1 Sensitivity analysis: correlation coefficient = 0.3 |
1 |
|
Odds Ratio (IV, Random, 95% CI) |
0.85 [0.33, 2.21] |
| 5.9 Sensitivity analysis: Adverse event: perforation/retraction, randomised by ear (medium‐term); CC = 0.7 |
1 |
|
Odds Ratio (IV, Random, 95% CI) |
0.91 [0.45, 1.86] |
| 5.9.1 Sensitivity analysis: correlation coefficient = 0.7 |
1 |
|
Odds Ratio (IV, Random, 95% CI) |
0.91 [0.45, 1.86] |
| 5.10 Sensitivity analysis: Persistence of OME: randomised by child (medium‐term); ICC = 1.0 |
1 |
40 |
Risk Ratio (M‐H, Random, 95% CI) |
0.27 [0.11, 0.70] |
| 5.10.1 Sensitivity analysis: assuming ICC of 1.0 (complete correlation between ears) |
1 |
40 |
Risk Ratio (M‐H, Random, 95% CI) |
0.27 [0.11, 0.70] |
| 5.11 Sensitivity analysis: Persistence of OME: randomised by child (medium‐term); ICC = zero |
1 |
81 |
Risk Ratio (M‐H, Random, 95% CI) |
0.30 [0.16, 0.56] |
| 5.11.1 Sensitivity analysis: assuming ICC of 0.0 (no correlation between ears) |
1 |
81 |
Risk Ratio (M‐H, Random, 95% CI) |
0.30 [0.16, 0.56] |
| 5.12 Sensitivity analysis: Persistence of OME: randomised by ear (medium‐term); CC = 0.3 |
1 |
|
Odds Ratio (IV, Random, 95% CI) |
0.66 [0.24, 1.83] |
| 5.12.1 Sensitivity analysis: correlation coefficient = 0.3 |
1 |
|
Odds Ratio (IV, Random, 95% CI) |
0.66 [0.24, 1.83] |
| 5.13 Sensitivity analysis: Persistence of OME: randomised by ear (medium‐term); CC = 0.7 |
1 |
|
Odds Ratio (IV, Random, 95% CI) |
0.66 [0.24, 1.83] |
| 5.13.1 Sensitivity analysis: correlation coefficient = 0.7 |
1 |
|
Odds Ratio (IV, Random, 95% CI) |
0.66 [0.24, 1.83] |
