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. 2023 Jul 21;36(12):651–659. doi: 10.1093/ajh/hpad068

Table 2.

Age and sex adjusted trends in characteristics of middle-aged adults, 2009–2018 (n = 9,783)

2009–2010 2011–2012 2013–2014 2015–2016 2017–2018 P for trend
Unweighted sample number 2,141 1,795 2,057 1,947 1,843
SBP, mean (SE) 119.6 (118.7–120.6) 120.8 (119.4–122.2) 120.4 (119.3–121.5) 122.6 (121.4–123.7) 122.5 (121.3–123.8) <0.0001
DBP, mean (SE) 73.1 (71.8–74.3) 74.5 (73.8–75.2) 73.2 (72.6–73.8) 74.2 (73.1–75.2) 76.6 (75.5–77.7) 0.0004
Hypertension, % (95% CI) 45.7 (41.1–50.3) 48.1 (45.7–50.5) 43.6 (40.5–46.6) 49.3 (46.4–52.2) 48.9 (45.0–52.8) 0.23
Cannabis use, % (95% CI)
 Never 43.8 (38.4–49.2) 41.1 (35.5–46.7) 41.7 (38.1–45.4) 44.3 (39.6–49.1) 43.1 (39.6–46.5) 0.80
 No history of monthly use 31.9 (28.0–35.7) 32.6 (27.5–37.6) 33.8 (30.6–37.0) 29.8 (26.7–32.9) 33.2 (28.3–38.0) 0.98
 History of monthly use 24.4 (21.4–27.3) 26.3 (22.4–30.3) 24.5 (20.6–28.3) 25.8 (22.2–29.5) 23.8 (20.2–27.4) 0.75
  <5 y of monthly use 6.3 (5.1–7.5) 5.3 (3.9–6.6) 5.4 (3.8–7.0) 4.8 (3.8–5.8) 4.5 (2.6–6.4) 0.10
  5–10 y of monthly use 4.8 (3.6–6.0) 5.0 (3.4–6.6) 3.8 (2.8–4.8) 5.8 (3.9–7.7) 3.8 (2.2–5.4) 0.62
  >10 y of monthly use 16.1 (13.3–18.9) 15.3 (11.4–19.2) 15.2 (12.1–18.3) 15.5 (12.5–18.5) 13.3 (10.8–15.7) 0.42
Sociodemographics, % (95% CI)
 Sex—female 49.4 (47.5–51.4) 49.9 (45.6–54.3) 51.3 (49.3–53.4) 51.4 (49.2–53.6) 51.2 (48.5–53.9) 0.2410
 Age (YOA), mean (SE) 46.9 (46.6–47.3) 47.4 (46.8–48.0) 47.1 (46.7–47.6) 47.2 (46.7–47.8) 47.6 (47.0–48.2) 0.1698
 Race/ethnicity
  Non-Hispanic White 69.7 (62.6–76.7) 67.6 (59.6–75.6) 65.6 (58.9–72.4) 64.2 (55.4–73.1) 59.6 (53.7–65.6) 0.0355
  Non-Hispanic Black, Asian and other 10.7 (8.8–12.7) 18.5 (12.5–24.5) 18.7 (15.1–22.3) 19.7 (13.9–25.5) 22.4 (17.7–27.2) 0.0004
  Hispanic (Inc. Mex. American) 19.6 (13.0–26.3) 13.9 (9.3–18.5) 15.7 (10.4–20.9) 16.1 (10.5–21.7) 17.9 (13.7–22.2) 0.9065
 Education
  High school or less 39.4 (36.1–42.6) 36.4 (30.3–42.5) 35.0 (29.0–41.0) 33.4 (27.3–39.4) 34.9 (30.3–39.5) 0.1046
  Some college 28.6 (26.6–30.5) 30.1 (27.1–33.0) 31.0 (28.1–33.9) 32.9 (29.4–36.3) 32.3 (29.0–35.5) 0.0256
  College graduate or above 31.9 (28.5–35.3) 33.5 (27.7–39.3) 34.0 (27.9–0.40.0) 33.8 (26.5–41.0) 32.8 (27.1–38.6) 0.8098
 Household income, annual $
  $0–44,999 33.1 (29.3–36.8) 36.3 (30.4–42.2) 33.1 (25.9–40.2) 27.8 (23.0–32.6) 30.4 (27.0–33.8) 0.0367
  $45,000–99,999 37.9 (33.4–42.4) 33.7 (28.6–38.8) 32.4 (29.5–35.4) 35.9 (31.9–39.9) 32.3 (27.8–36.8) 0.2258
  ≥$100,000 29.1 (25.4–32.8) 30.0 (22.1–38.0) 34.5 (27.3–41.7) 36.3 (28.8–43.9) 37.3 (31.4–43.2) 0.0129
Lifestyle, behavioral, % (95% CI)
 Alcohol use
  No d/wk 16.0 (13.7–18.3) 15.8 (12.3–19.4) 13.9 (11.1–16.6) 15.1 (13.6–16.6) 15.9 (13.2–18.6) 0.8545
  ≤2 d/wk 61.3 (57.7–64.9) 59.8 (56.4–63.1) 65.6 (61.9–69.2) 64.3 (60.4–68.2) 69.8 (66.8–72.8) 0.0001
  >2 d/wk 22.7 (20.1–25.4) 24.4 (19.2–29.7) 20.6 (17.2–24.0) 20.6 (16.6–24.7) 14.3 (12.0–16.6) <0.0001
 Cigarette smoking status
  Never 21.4 (19.5–23.3) 23.8 (20.3–27.2) 21.8 (18.6–25.0) 21.2 (18.1–24.4) 20.3 (17.1–23.6) 0.2817
  Past 23.5 (19.9–27.0) 22.9 (19.5–26.3) 21.7 (19.0–24.4) 24.1 (21.2–27.0) 22.6 (19.5–25.7) 0.9262
  Current 55.1 (51.4–58.9) 53.3 (50.1–56.5) 56.5 (52.3–60.6) 54.6 (51.1–58.2) 57.1 (52.4–61.7) 0.4173
Cigarette smoking pack-years, mean (SE) 7.2 (6.4–8.0) 7.0 (6.1–7.9) 6.7 (5.5–7.8) 7. 5 (6.5–8.5) 5.4 (4.0–6.8) 0.0680
Physical activity (min/wk), mean (SE) 344.4 (308.7–380.2) 365.1 (327.4–402.8) 336.7 (308.3–365.1) 333.2 (308.3–358.1) 316.4 (283.7–349.1) 0.1085
BMI, kg/m2, mean (SE) 29.2 (28.9–29.5) 29.4 (28.9–30.0) 29.8 (29.12–30.5) 30.0 (29.3–30.8) 30.5 (30.0–31.0) 0.0001
 Weight
  Under/normal: BMI <25 26.7 (23.5–29.9) 25.5 (22.3–28.6) 24.7 (22.3–27.1) 24.6 (20.8–28.3) 22.7 (19.8–25.7) 0.0820
  Overweight: BMI 25 to <30 35.3 (32.3–38.4) 35.7 (32.2–39.2) 33.4 (30.2–36.6) 32.2 (28.9–35.4) 32.1 (28.9–35.3) 0.0500
  Obese: BMI ≥30 37.6 (35.5–39.6) 38.4 (35.2–41.6) 41.2 (37.1–45.3) 42.9 (37.5–48.2) 44.7 (41.5–47.9) 0.0003
Cardiometabolic medical history, % (95% CI)
 Dyslipidemia 34.1 (32.6–35.7) 33.7 (30.6–36.8) 33.9 (31.1–36.7) 31.9 (29.0–34.9) 27.3 (24.7–29.8) <0.0001
 Antilipidemic medication 13.7 (12.0–15.4) 14.2 (11.4–17.0) 16.0 (13.1–19.0) 12.5 (9.8–15.3) 12.0 (9.4–14.5) 0.1563
 Diabetes or prediabetes 44.0 (41.6–46.3) 43.8 (39.8–47.8) 39.2 (35.3–43.1) 47.8 (44.0–51.6) 51.6 (47.6–55.5) 0.0004
 Antidiabetic medication 5.6 (4.2–7.0) 7.0 (5.4–8.7) 8.6 (6.7–10.4) 7.8 (6.3–9.3) 9.1 (6.9–11.4) 0.0097

Notes: Subgroups by year are represented by weighted percentages and 95% confidence intervals or weighted means with 95% confidence intervals. All comparisons are adjusted for age and sex, except for age, which is adjusted for sex, and sex, which is adjusted for age. P values for tests of trends are derived from multiple linear regression models using dummy variables for each level of categorical variable. Physical activity includes the following domains: Walk/bike for transportation, vigorous recreational, moderate recreational. Cannabis use variables are all standard NHANES variables, other than Years of Monthly Use, which was calculated. Abbreviations: BMI, body mass index; CI, confidence interval; DBP, diastolic blood pressure; NHANES, National Health and Nutrition Examination Survey; SBP, systolic blood pressure.

*Designates P < 0.05.