Table 1.
Comparison of the baseline characteristics of the CC + letrozole and CC-alone groups
| Characteristic | Letrozole + CC group (n = 50) | Clomiphene citrate group (n = 50) | P-values |
|---|---|---|---|
| Age (years), mean ± SD | 31.8 ± 4.6 | 32.4 ± 3.8 | 0.540 |
| BMI (kg/m2), mean ± SD | 23.5 ± 4.9 | 22.9 ± 3.5 | 0.456 |
| Fertility history | |||
| Previous live birth, n (%) | 5 (10.0%) | 2 (4.0%) | 0.436 |
| Previous abortion, n (%) | 13 (26.0%) | 7 (14.0%) | 0.211 |
| Duration of attempts to conceive (years), median (min, max) | 2 (1, 11) | 2 (1, 10) | 0.554 |
| Ovulatory disorders | |||
| PCOS | 24 (48.0%) | 22 (44.0%) | 0.841 |
| Unexplained ovulatory disorders | 26 (52.0%) | 28 (46%) | |
| Coexisting condition, n (%) | |||
| Endometriosis | 5 (10.0%) | 12 (24.0%) | 0.110 |
| Myoma uteri+ | 5 (10.0%) | 5 (10.0%) | 1.000 |
| Baseline total motile sperm count (millions), median (min, max) | 48.7 (10, 418) | 55.3 (10, 350) | 0.915 |
PCOS, polycystic ovary syndrome
+ Submucous or intramural myoma, distorted the uterine cavity
- None of the patients in either group had other coexisting conditions (pelvic inflammatory disease, autoimmune disease, and recurrent pregnancy loss)