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. 2023 Nov 15;21:811. doi: 10.1186/s12967-023-04713-3

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 4 — The Notch 5-TSPs signature is significantly associated with relapse-free survival in patients with TNBC within the METABRIC dataset. A Kaplan‒Meier survival analysis showing the association between the signature’s predictions and relapse-free survival in 157 patients with TNBC included in the METABRIC dataset. B Forest plot showing the results of multivariate survival analysis using the Cox proportional hazards model. The multivariate Cox model included the signature’s predictions together with T-stage, radiotherapy, age, type of surgery, and menopausal status. The hazard ratios and 95% confidence intervals are displayed. * denotes statistical significance