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. 2023 Nov 15;21:440. doi: 10.1186/s12916-023-03146-5

Table 3.

Results of confirmatory analysis

Task N Supplement effect
3-way ANOVA, inkl. diet
Supplement effect
2-way ANOVA
Crea. score Pl.
score
Crea.-Pl. scores
M(SE) [95% CI]
Total Crea. first Pl. first F (df) p η2P F (df) p η2P
BDS 121 61 60 3.41 (1, 117) 0.067 0.028 3.49 (1, 119) 0.064 0.029 8.85 (0.28) 8.44 (0.25) 0.41 (0.22) [–0.24; 0.84]
RAPM 118 60 58 1.02 (1, 114) 0.315 0.009 0.97 (1, 116) 0.327 0.008 12.39 (0.28) 12.16 (0.28) 0.23(0.23) [− 0.24; 0.70]

Mixed 3-way ANOVA with supplement (creatine vs placebo) as the within-subjects variable, supplement order (creatine-first vs placebo-first) and diet (vegetarian vs omnivore) as the between-subjects variable and test score after supplementation as the dependent variable. Mixed 2-way ANOVA without diet. The test score is given as estimated marginal mean (standard error). P-values are two-tailed. The two cognitive tasks are the Backward Digit Span and Raven’s Advanced Progressive Matrices