Table 2.
Two independent predictors of OS obtained from stepwise Cox regression analysis in the combine dataset
| Characteristics | Category | Frequency | HR (95% CI) | P a |
|---|---|---|---|---|
| Age (year) | ≤47 | 434 | 1.00 | |
| >47 | 432 | 0.80 (0.66-0.97) | 0.026 | |
| Sex | Female | 106 | 1.00 | |
| Male | 760 | 1.28 (0.93-1.77) | 0.135 | |
| AFP level (ng/ml) | ≤400 | 522 | 1.00 | |
| >400 | 344 | 1.30 (1.06-1.60) | 0.011 | |
| Embolus | No | 636 | 1.00 | |
| Yes | 230 | 1.72 (1.36-2.18) | <0.001 | |
| BCLC stage | 0/A | 427 | 1.00 | |
| B/C | 439 | 2.02 (1.59-2.57) | <0.001 | |
| SLC2A9 rs28643326 T>C | TT/TC/CC | 534/295/37 | 0.73 (0.61-0.88) | <0.001 |
| SLC5A10 rs2472711 G>T | GG/GT/TT | 261/397/208 | 0.81 (0.71-0.92) | 0.002 |
Abbreviations: OS: overall survival; HR: hazards ratio; 95% CI: 95% confidence interval; AFP: alpha-fetoprotein; BCLC: Barcelona Clinic Liver Cancer.
a Stepwise Cox regression analysis was adjusted for age, sex, smoking status, drinking status, AFP level, cirrhosis, embolus, and BCLC stage.