Table 3.
Adjusted geometric means (95% CI) of urinary 8-OHdG/creatinine levels according to OBS quartiles in Japanese men and women.
| OBS | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Q1 | Q2 | Q3 | Q4 | p for Trend a | ||||||
| Men | ||||||||||
| n (%) | 501 (16.2) | 816 (26.4) | 950 (30.8) | 819 (26.5) | ||||||
| Model 1 b | 4.12 | (3.96–4.29) | 3.76 | (3.65–3.88) | 3.69 | (3.59–3.80) | 3.30 | (3.20–3.41) | <0.01 | |
| Model 2 c | 4.12 | (3.96–4.29) | 3.77 | (3.65–3.89) | 3.70 | (3.59–3.81) | 3.29 | (3.19–3.40) | <0.01 | |
| Model 3 d | 4.14 | (3.98–4.31) | 3.78 | (3.66–3.90) | 3.69 | (3.59–3.80) | 3.28 | (3.17–3.38) | <0.01 | |
| Women | ||||||||||
| n (%) | 873 (19.5) | 1312 (29.3) | 776 (17.4) | 1511 (33.8) | ||||||
| Model 1 | 4.53 | (4.38–4.68) | 4.26 | (4.14–4.37) | 4.17 | (4.02–4.32) | 3.75 | (3.65–3.84) | <0.01 | |
| Model 2 | 4.47 | (4.33–4.61) | 4.25 | (4.15–4.36) | 4.16 | (4.02–4.30) | 3.78 | (3.69–3.87) | <0.01 | |
| Model 3 | 4.49 | (4.35–4.63) | 4.25 | (4.02–4.29) | 4.16 | (4.02–4.29) | 3.77 | (3.69–3.86) | <0.01 | |
OBS: oxidative balance score; CI: confidence interval; 8-OHdG: 8-hydroxydeoxyguanosine. a Trend tests were performed by including the ordinal numbers 0 to 3 assigned to each quartile category of the OBS in a multiple linear regression analysis. b Unadjusted. c Adjusted for age (years, continuous), total energy intake (kcal, continuous), hypertension (category), diabetes mellitus (category), dyslipidemia (category), and menopausal status (in women only, category). d Adjusted for age (years, continuous), total energy intake (kcal, continuous), hypertension (category), diabetes mellitus (category), dyslipidemia (category), menopausal status (in women only, category), and body mass index (kg/m2, continuous).