Table A5.
The distribution of the alleles HLA-A, -B, -DRB1, -DQA1, -DQB1 and -DPB1 in IgA nephropathy (IgAN) patients and healthy donors.
| Allele | IgAN (%) | Control (%) | p’ (chi-sq) | p’ (Fisher’s Exact Test) | OR | 95% CI |
|---|---|---|---|---|---|---|
| A*02:01:01G | 30.00 | 27.13 | >0.05 | 1.151 | 0.777–1.682 | |
| A*24:02:01G | 16.43 | 10.98 | >0.05 | 1.594 | 0.961–2.543 | |
| A*01:01:01G | 9.29 | 12.14 | >0.05 | 0.741 | 0.381–1.327 | |
| A*03:01:01G | 8.57 | 13.95 | >0.05 | 0.578 | 0.289–1.055 | |
| A*31:01:02G | 5.71 | 2.00 | >0.05 | 2.967 | 1.210–6.327 | |
| B*35:01:01G | 9.29 | 6.35 | >0.05 | 1.508 | 0.770–2.725 | |
| B*27:05:02G | 7.14 | 3.87 | >0.05 | 1.912 | 0.877–3.734 | |
| B*56:01:01G | 5.71 | 1.38 | >0.05 | 4.331 | 1.739–9.437 | |
| B*51:01:01G | 5.71 | 5.19 | >0.05 | 1.107 | 0.461–2.291 | |
| B*07:02:01G | 5.71 | 11.79 | >0.05 | 0.454 | 0.190–0.929 | |
| C*04:01:01G | 16.43 | 12.41 | >0.05 | 1.387 | 0.837–2.210 | |
| C*01:02:01G | 11.43 | 4.52 | 0.029 | 2.727 | 1.477–4.738 | |
| C*02:02:02G | 10.00 | 6.06 | >0.05 | 1.723 | 0.901–3.0621 | |
| C*06:02:01G | 9.29 | 11.95 | >0.05 | 0.754 | 0.387–1.351 | |
| C*03:04:01G | 6.43 | 5.16 | >0.05 | 1.261 | 0.556–2.521 | |
| DRB1*01:01:01G | 40.00 | 10.25 | 0.034 | 2.189 | 1.373–3.389 | |
| DRB1*03:01:01G | 9.29 | 7.73 | >0.05 | 1.221 | 0.625–2.120 | |
| DRB1*13:01:01G | 8.57 | 6.92 | >0.05 | 1.260 | 0.626–2.319 | |
| DRB1*07:01:01G | 7.86 | 13.36 | >0.05 | 0.553 | 0.267–1.033 | |
| DRB1*11:04:01G | 6.43 | 4.87 | >0.05 | 1.343 | 0.591–2.686 | |
| DQA1*05:01:01G | 30.00 | 24.64 | >0.05 | 1.310 | 0.869–1.949 | |
| DQA1*01:01:01G | 28.57 | 16.51 | 0.0076 | 2.021 | 1.322–3.048 | |
| DQA1*03:01:01G | 17.86 | 11.40 | >0.05 | 1.689 | 1.012–2.733 | |
| DQA1*01:03:01G | 10.00 | 9.13 | >0.05 | 1.105 | 0.567–2.009 | |
| DQA1*02:01:01G | 7.86 | 13.41 | >0.05 | 0.551 | 0.262–1.048 | |
| DQB1*03:01:01G | 26.43 | 22.12 | >0.05 | 1.265 | 0.837–1.875 | |
| DQB1*05:01:01G | 24.29 | 13.12 | 0.01 | 2.124 | 1.383–3.195 | |
| DQB1*02:01:01G | 14.29 | 18.39 | >0.05 | 0.740 | 0.433–1.204 | |
| DQB1*06:03:01G | 8.57 | 7.17 | >0.05 | 1.214 | 0.603–2.233 | |
| DQB1*03:02:01G | 7.14 | 7.22 | >0.05 | 0.988 | 0.458–1.906 | |
| DPB1*04:01:01G | 32.14 | 44.19 | >0.05 | 0.598 | 0.408–0.868 | |
| DPB1*04:02:01G | 22.14 | 13.44 | >0.05 | 1.831 | 1.174–2.786 | |
| DPB1*02:01:02G | 15.71 | 14.66 | >0.05 | 1.086 | 0.649–1.740 | |
| DPB1*03:01:01G | 10.00 | 9.84 | >0.05 | 1.018 | 0.535–1.795 | |
| DPB1*06:01:01G | 3.57 | 1.43 | >0.05 | 2.546 | 0.782–6.470 |
Notes: chi-sq—basic allelic test chi-square (1df), OR—odds ratio for Fisher’s exact test and basic allelic test chi-square, 95% CI—odds ratio and confidence interval for odds ratio for Fisher’s exact test and basic allelic test chi-square, p’—Bonferroni single-step adjusted p-values.