Skip to main content
. 2023 Oct 26;16(21):6881. doi: 10.3390/ma16216881

Table 7.

Distinct types of genotoxicity tests, summarized from [65].

Type of Test Description
Ames Test Detects point mutations using Salmonella typhimurium bacterial strains sensitive to mutagens.
Mouse Lymphoma Assay It uses mammalian cells to detect point mutations and can detect clastogenic lesions in genes.
HGPRT Assay It uses mammalian cells to detect point mutations.
Unscheduled DNA Synthesis (UDS) Assay Detects DNA damage and repair using both in vitro and in vivo methods.
Chromosomal Aberration Assay Allows direct observation of chromosome damage using both in vitro and in vivo methods.
Mouse Micronucleus Assay Detects chromosome damage using mammalian cells.