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Time-dependent internalization of [99mTc]Tc-DT10 (●, green lines), [99mTc]Tc-DT11 (■, violet lines), [99mTc]Tc-DT12 (♦, brown lines) and [99mTc]Tc-DT1 (reference; ▲, gray lines) in AsPC-1 cells; solid lines correspond to internalized and dotted lines to membrane bound fractions, in all cases. Results represent average values ± sd (n = 3, in triplicate; specific values are included, determined by subtracting non-specifics (found in the presence of 1 μM of NT) from totals).
