Table 2.
Prevalence of SNPs in the AOC1 gene in patients with LUTS.
| Genetic Profile | Total Patients (n = 100) |
Men (n = 46) |
Women (n = 54) |
p Value | |
|---|---|---|---|---|---|
| SNPs minor allele, n (%) | |||||
| 0 | 12 (12.0) | 4 (8.7) | 8 (14.8) | 0.808 | |
| 1 | 20 (20.0) | 8 (17.4) | 12 (22.2) | ||
| 2 | 22 (22.0) | 11 (23.9) | 11 (20.4) | ||
| 3 | 15 (15.0) | 7 (15.2) | 8 (14.8) | ||
| 4 | 31 (31.0) | 16 (34.8) | 15 (27.8) | ||
| SNPs genotype, n (%) | |||||
| rs2052129 (c.691G>T) |
GG | 39 (39.0) | 17 (36.9) | 22 (40.7) | 0.816 |
| GT | 58 (58.0) | 28 (60.9) | 30 (55.6) | ||
| TT | 3 (3.0) | 1 (2.2) | 2 (3.7) | ||
| rs10156191 (p.Thr16Met) |
CC | 34 (34.0) | 14 (30.4) | 20 (37.0) | 0.742 |
| CT | 61 (61.0) | 30 (65.2) | 31 (57.4) | ||
| TT | 5 (5.0) | 2 (4.3) | 3 (5.6) | ||
| rs1049742 (p.Ser332Phe) |
CC | 43 (43.0) | 24 (52.2) | 29 (53.7) | 0.912 |
| CT | 56 (56.0) | 22 (47.8) | 24 (44.4) | ||
| TT | 1 (1.0) | 0 | 1 (1.1) | ||
| rs1049743 (p.His664Asp) |
CC | 41 (41.0) | 14 (30.4) | 27 (50.0) | 0.046 |
| CG | 53 (53.0) | 27 (58.7) | 26 (48.1) | ||
| GG | 6 (6.0) | 5 (10.9) | 1 (1.9) | ||