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. 2023 Oct 31;12(21):6870. doi: 10.3390/jcm12216870

Table 5.

Severity of storage and voiding scores of the IPSS questionnaire and SNP genotype.

Variables S-IPSS Score Allele Positivity
Odds Ratio
(95% Confidence Interval)
V-IPSS Allele Positivity
Odds Ratio
(95% Confidence Interval)
Mild/
Moderate
<20, n (%)
Severe
≥20, n (%)
Mild/
Moderate
<20, n (%)
Severe
≥20, n (%)
Gender Male 36 (78.3) 10 (21.7) 2.29 (0.94–5.57); p = 0.065 38 (82.6) 8 (17.4) 0.28 (0.07–1.12); p = 0.059
Female 33 (61.1) 21 (38.9) 51 (94.4) 3 (5.6)
rs2052129
(c.691G>T)
GG 29 (74.4) 10 (25.6) 1.52 (0.62–3.71); p = 0.354 39 (100.0) 0 17.0 (1.03–314.7); p = 0.006 *
GT-TT 40 (65.6) 21 (34.4) 50 (82.0) 11 (18.0)
rs10156191
(p.Thr16Met)
CC 26 (76.5) 8 (23.5) 1.74 (0.68–4.45); p = 0.246 34 (100.0) 0 14.3 (0.82–250.4); p = 0.014 *
CT-TT 43 (65.2) 23 (34.8) 55 (83.3) 11 (16.7)
rs1049742
(p.Ser332Phe)
CC 38 (71.7) 15 (28.3) 1.31 (0.56–3.06); p = 0.536 50 (94.3) 3 (5.7) 3.42 (0.85–13.75); p = 0.070
CT-TT 31 (66.0) 16 (34.0) 39 (83.0) 8 (17.0)
rs1049743
(p.His664Asp)
CC 26 (63.4) 15 (36.6) 0.64 (0.27–1.52); p = 0.314 38 (92.7) 3 (7.3) 1.99 (0.49–7.99); p = 0.518
CG-GG 43 (72.9) 16 (27.1) 51 (86.4) 3 (16.3)
rs2052129
rs10156191
No 31 (73.8) 11 (26.2) 1.48 (0.62–3.56); p = 0.376 42 (100.0) 0 20.58 (1.86–359.9); p = 0.002 *
Yes 38 (65.5) 20 (34.5) 47 (81.0) 11 (19.0)
SNPs < 4 SNPs 50 (72.5) 19 (27.5) 1.66 (0.68–4.07); p = 0.264 65 (94.2) 4 (5.8) 4.74 (1.27–17.65); p = 0.032
4 SNPs 19 (61.3) 12 (38.7) 15 (48.4) 16 (51.6)
Homozygosity No 61 (70.1) 26 (29.9) 1.47 (0.44–4.90); p = 0.534 80 (92.0) 7 (8.0) 5.08 (1.24–20.77); p = 0.035
Yes 8 (61.5) 5 (38.5) 9 (69.2) 4 (30.8)

S-IPSS: storage subscale of the International Prostate Symptom Score; V-IPSS: voiding subscale of the International Prostate Symptom Score; * Estimated odds ratio with the Haldane–Anscombe correction or Fisher’s exact test.