NEN	neuroendocrine neoplasm
NET	neuroendocrine tumor
NEC	neuroendocrine carcinoma
GEP-NET	gastrointestinal neuroendocrine tumor
panNET	pancreatic neuroendocrine tumor
SI-NETs	small intestine neuroendocrine tumor
TME	tumor microenvironment
CT	computed tomography
MRI	magnetic resonance imaging
EUS	endoscopic ultrasound
SSA	somatostatin analog
PET	positron emission tomography
mTOR	mammalian target of rapamycin
TKI	tyrosine kinase inhibitor
IHC	immunohistochemistry
IF	immunofluorescence
FFPE	formalin-fixed paraffin-embedded
PD-1	programmed cell death-1
PD-L1	programmed cell death-1 ligand
SHP-2	homology region 2 domain-containing phosphatase (SHP-2)
TAM	tumor-associated macrophages
TIL	tumor-infiltrating lymphocyte
RT-PCR	reverse transcription polymerase chain reaction
HHLA2	human endogenous retrovirus H long terminal repeat-associating 2
B7x	B7 homolog x
HIF-1α	hypoxia-inducible factor 1 alpha
FOXM1	Forkhead box protein M1
IGF1R	type 1 insulin-like growth factor receptor
HLA	human leukocyte antigen
TNF-α	tumor necrosis factor alpha
VEGF	vascular endothelial growth factor
IDO	indoleamine 2,3-dioxygenase
TDO	tryptophan 2,3-dioxygenase
B7-H3	B7 homolog 3 protein
OS	overall survival
PFS	progression-free survival.
CTLA-4	cytotoxic T-lymphocyte-associated protein-4
CAF	cancer-associated fibroblast
VASH-1	vasohibin-1
MDSC	myeloid-derived suppressor cells
FCM	flow cytometry
irAEs	immune-related adverse events