Table 1.
15q11-q13 inversion status and evolution in human and NHPs.
| Species | BP1-BP2 Inversion chr15:20454276-21173858 |
BP2-BP3 Inversion chr15:21173858-25860219 |
BP3-BP5 Inversion chr15:26608046-29923396 |
BP3-BP4 Inversion chr15:26617330-27847082 |
BP4-BP5 Inversion chr15:28677026-29923396 |
|---|---|---|---|---|---|
| Homo sapiens | dir/dir | dir/inv | dir/dir | dir/dir | dir/inv |
| Pan troglodytes | dir/dir | dir/dir | n.a. * | inv/inv | dir/dir |
| Gorilla gorilla | dir/dir | dir/dir | dir/dir | dir/inv | inv/inv |
| Pongo pygmaeus | inv/inv | inv/inv | dir/dir | inv/inv | dir/dir |
| Macaca mulatta | inv/inv | inv/inv | inv/inv | dir/dir | dir/dir |
| Callithrix jacchus (outgroup) | inv/inv | inv/inv | inv/inv | dir/dir | inv/inv |
| Evolution | African great ape ancestor |
African great ape ancestor |
Great apes ancestor |
Great apes ancestor |
Catharrini ancestor |
* not tested because the region is interrupted by a Pan-specific inversion. dir = direct orientation; inv = inverted orientation. Coordinates are based on the T2T CHM13v2.0/hs1 reference. Coordinates are based on the T2T CHM13v2.0/hs1 reference.