Table 5.
Inhibitory effects of Pulicaria incisa extracts on AChE, BChE, and α-amylase and α-glucosidase.
| IC50 (µg/mL) | ||||
|---|---|---|---|---|
| AChE | BChE | α-Amylase | α-Glucosidase | |
| Pulicaria incisa (aqueous extract) | 1621.5 ± 109.6 b | 1092.5 ± 6.4 b | n.a. | 393.9 ± 39.9 a |
| Pulicaria incisa (methanolic extract) | 292.3 ± 1.5 a | 236.9 ± 15.7 a | n.a. | 1936.5 ± 164.7 b |
| Galantamine | 0.9 ± 0.4 | 4.6 ± 1.5 | – | – |
| Acarbose | – | – | 11 ± 4.2 | 963 ± 0.8 |
Results are reported as the means ± SD of three experiments. Different letters indicate mean values significantly different at p < 0.05, according to a one-way ANOVA followed by Tukey’s post hoc test. n.a. = not active (IC50 > 10,000 µg/mL).