Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Nov 15;3(11):2312–2330. doi: 10.1158/2767-9764.CRC-23-0140

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2023 The Authors; Published by the American Association for Cancer Research

This open access article is distributed under the Creative Commons Attribution 4.0 International (CC BY 4.0) license.

PMC Copyright notice

snRNA-seq of Patient HL-248. A, UMAP representation of unsupervised clustering of nuclei sequenced in HL-248. B, UMAP of HL-248 clusters with cell-type labels determined by celldex and SingleR. C, UMAP of HL-248 where highlighted nuclei are nuclei with a VAF > 0 for the EIF4A2 variant uncovered in this sample's deep exome (chr3:186783634 T/A). D, UMAP of HL-248 where highlighted nuclei are nuclei that express an expanded BCR clonotype. E, Genes differentially expressed between cluster 3 and all other B cells are displayed as either downregulated with a significant P value (blue) or upregulated with a significant P value (orange).