ADC |
Antibody–drug conjugate |
AE(s) |
Adverse event(s) |
bAbs |
Bispecific antibodies |
BC |
Breast cancer |
ECD |
Extracellular domain |
EGFR |
Epidermal growth factor receptor |
ER + |
Estrogen receptor positive |
ESCC |
Esophageal squamous cell carcinoma |
HER2 + |
HER2-amplified |
HNSCC |
Head and neck squamous cell carcinoma |
HRG |
Heregulin |
IGF1R |
Insulin-like growth factor 1 receptor |
IMA |
Invasive mucinous adenocarcinomas |
MoAbs |
Monoclonals antibodies |
NRG(s) |
Neuregulin(s) |
NSCLC |
Non-small cell lung cancers |
OS |
Overall survival |
PD-1 |
Programmed cell death-1 |
PFS |
Progression-free survival |
PR |
Partial response |
RAI |
Radioactive iodine |
RP2D |
Recommended phase 2 dose |
RTK |
Receptor tyrosine kinases |
scDb |
Bispecific single-chain diabody |
T-DM1 |
Trastuzumab-emtansine |
TKIs |
Tyrosine kinase inhibitors |
TNBC |
Triple-negative breast cancer |