Table 5.

Effect estimates for the impact of amyloid status on EQ-5D utility trajectory

Variable	Estimates (SE)	P value
Clinical stage × time		0.27
SCD × time	Reference
MCI × time	0.003 (0.003)
Dementia × time	0.007 (0.012)
Clinical stage × amyloid		0.79
SCD × amyloid positive	Reference
MCI × amyloid positive	0 (0.021)
DEM × amyloid positive	0.031 (0.048)
Time × amyloid positive	− 0.011 (0.004)	< 0.05
Clinical stage × time × amyloid		0.95
SCD × time × amyloid positive	Reference
MCI × time × amyloid positive	0.002 (0.006)
Dementia × time × amyloid positive	0.003 (0.014)

Model adjusted for baseline age, sex, education, and BMI

SCD Subjective cognitive decline, MCI Mild cognitive impairment