Table 1.

Semiquantitative evaluation of the density of CB1R, CB2R, TRPV1, GPR55, and PPAR-gamma immunoreactivity in different cellular elements of the equine trigeminal ganglia. The immunoreactive cells were graded as: −, negative; +, faint; ++, moderate; +++, bright. Abbreviations: Cryo, cryosections; FFPE, formalin fixed paraffin embedded sections, IF, immunofluorescence; IHC, immunohistochemistry.

Receptors	CB1R	CB2R	TRPV1	GPR55	PPAR-ƴ
Neurons	+ IF Cryo + IHC iFFPE	++ IF Cryo ++ IHC FFPE	+++ IF Cryo +++ IHC FFPE	+/− IF Cryo ++/+++ IHC FFPE	+++ IF Cryo +++ IHC FFPE
Satellite glial cells	− IF Cryo − IHC FFPE	++ IF Cryo +++ IHC FFPE	− IF Cryo − IHC FFPE	− IF Cryo ++ IHC FFPE	+++ IF Cryo +++ IHC FFPE
Inflammatory or immune cells	− IF Cryo − IHC FFPE	− IF Cryo − IHC FFPE	− IF Cryo − IHC FFPE	− IF Cryo +++ IHC FFPE	+++ IF Cryo +++ IHC FFPE