Table 1.
Pooled prevalence of non-alcoholic fatty liver disease (NAFLD) in patients with inflammatory bowel disease (IBD) overall, Crohn’s disease and ulcerative colitis according to sex, type of publication and study design. Prevalence of metabolic (dysfunction-) associated fatty liver disease (MAFLD) in the same groups of patients.
| Inflammatory Bowel Disease | Crohn’s Disease | Ulcerative Colitis | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| n | Proportion (95%CI) | I2 | n | Proportion (95%CI) | I2 | n | Proportion (95%CI) | I2 | ||
| NAFLD | 68 | 24.4 (19.3–29.8) | 99.7 | 46 | 20.2 (18.30–22.27) | 99.7 | 41 | 18.52 (16.36–20.79) | 99.5 | |
| Male | 15 | 28 (14.5–44) | 99.5 | 7 | 27.5 (9.1–51.2) | 99.2 | - | - | - | |
| Female | 15 | 22.5 (11.6–35.9) | 99.4 | 7 | 24.2 (7–47.6) | 98.8 | - | - | - | |
| Full paper | 29 | 27.5 (20.3–35.3) | 99.3 | 26 | 26.2 (19.0–34.1) | 98.7 | 23 | 24 (16.1–32.9) | 99 | |
| Abstract | 39 | 22.1 (15.2–29.9) | 99.7 | 20 | 12.7 (10.9–14.6) | 99.7 | 18 | 12.4 (10.4–14.4) | 99.5 | |
| Prospective | 15 | 24.3 (13.6–37.7) | 99 | 7 | 22 (6.4–4.4) | 98.8 | 10 | 19.9 (9.2–33.5) | 97.7 | |
| Retrospective | 46 | 23.2 (17.2–29.9) | 99.8 | 32 | 19 (16.9–21.3) | 99.7 | 25 | 17.3 (14.9–19.9) | 99.6 | |
| Cross-sectional | 7 | 32.5 (7.9–64.1) | 99.7 | 7 | 25.6 (4.6–56.1) | 99.5 | 6 | 23.6 (3.4–54.2) | 99.5 | |
| MAFLD | 19 | 30.4 (21.9–39.6) | 96.2 | 9 | 40 (25.4–55.5) | 99.4 | 4 | 53.6 (13.8–90.8) | 99.5 | |