Figure 2.

Mechanisms of drug resistance reversal through ferroptosis targeting. This figure illustrates diverse molecular interactions and sites of action for various agents aimed at reversing drug resistance through ferroptosis modulation. In the diagram, red text denotes sites of action for agents targeting ferroptosis reversal in chemotherapy, blue text represents sites of action for agents targeting ferroptosis reversal specifically, and green text indicates sites of action for agents targeting ferroptosis reversal in immunotherapy. The integrated approach to targeting these pathways highlights their potential synergistic effects in overcoming drug resistance. The figures were created using the Figdraw software (https://www.figdraw.com, accessed on 13 August 2023).