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Synergy scores of pomotrelvir (PBI-0451) in combination with remdesivir or NHC as analyzed by four synergy methods a
| Synergy score by | PBI-0451xRDV | PBI-0451xNHC |
|---|---|---|
| ZIP | 3.1 | 0.5 |
| HSA | 3.2 | 3.8 |
| Loewe | 7.0 | 1.7 |
| Bliss | 4.8 | 0.8 |
RDV, remdesivir; NHC, N4-hyroxycytidine; HSA, highest single agent; ZIP, zero interaction potency.
