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Prevention of endothelial damage induced by serum (severe P. falciparum malaria) and neutrophils. Shown are results with TUNEL-positive endothelial cell nuclei after incubation with gabexate mesilate (a), pentoxifylline (b), ascorbic acid (c), tocopherol (d), ulinastatin (e), and ascorbic acid plus ulinastatin (f). Each of these graphs shows one representative experiment out of three. Means (bars) and individual results (whiskers) of duplicate assays are shown.
